4L7R
Human artd3 (parp3) - catalytic domain in complex with inhibitor ME0400
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Poly [ADP-ribose] polymerase 3 | polymer | 357 | 39752.1 | 1 | UniProt (Q9Y6F1) Pfam (PF02877) Pfam (PF00644) In PDB | Homo sapiens (human) | PARP-3, hPARP-3, ADP-ribosyltransferase diphtheria toxin-like 3, ARTD3, IRT1, NAD(+) ADP-ribosyltransferase 3, ADPRT-3, Poly[ADP-ribose] synthase 3, pADPRT-3 |
| 2 | A | N-[(2S)-1-hydroxybutan-2-yl]-3-(4-oxo-3,4-dihydroquinazolin-2-yl)propanamide | non-polymer | 289.3 | 1 | Chemie (M00) | |||
| 3 | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A: 178 - 532 (UniProt: Q9Y6F1)
| PDB | External Database | Details |
|---|---|---|
| Ser 176 | - | expression tag |
| Met 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39752.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 289.3 | |
| All* | Total formula weight | 40041.4 |
