4L6R
Structure of the class B human glucagon G protein coupled receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Soluble cytochrome b562 and Glucagon receptor chimera | polymer | 425 | 48150.8 | 1 | UniProt (P0ABE7) UniProt (P47871) Pfam (PF07361) Pfam (PF00002) | Escherichia coli (human) | Cytochrome b-562, GL-R |
| 2 | B (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) |
Sequence modifications
A: 1001 - 1106 (UniProt: P0ABE7)
A: 123 - 432 (UniProt: P47871)
| PDB | External Database | Details |
|---|---|---|
| Trp 1007 | Met 29 | engineered mutation |
| Ile 1102 | His 124 | engineered mutation |
| Leu 1106 | Arg 128 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 433 | - | SEE REMARK 999 |
| Arg 434 | - | SEE REMARK 999 |
| Pro 435 | - | SEE REMARK 999 |
| Leu 436 | - | SEE REMARK 999 |
| Glu 437 | - | SEE REMARK 999 |
| Val 438 | - | SEE REMARK 999 |
| Leu 439 | - | SEE REMARK 999 |
| Phe 440 | - | SEE REMARK 999 |
| Gln 441 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 48150.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 106.1 | |
| All* | Total formula weight | 48257.0 |
