4L6Q
ROCK2 in complex with benzoxaborole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Rho-associated protein kinase 2 | polymer | 402 | 45900.1 | 2 | UniProt (O75116) Pfam (PF00069) In PDB | Homo sapiens (human) | Rho kinase 2, Rho-associated, coiled-coil-containing protein kinase 2, ROCK-II, p164 ROCK-2 |
| 2 | A, B | 6-[4-(aminomethyl)-2-fluorophenoxy]-2,1-benzoxaborol-1(3H)-ol | non-polymer | 273.1 | 2 | Chemie (1WU) | |||
| 3 | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A, B: 19 - 417 (UniProt: O75116)
| PDB | External Database | Details |
|---|---|---|
| Gly 16 | - | expression tag |
| Ala 17 | - | expression tag |
| Ala 18 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 91800.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 546.1 | |
| All* | Total formula weight | 92346.4 |
