4L5A
Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with tubercidin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | S-methyl-5'-thioadenosine phosphorylase | polymer | 320 | 35259.5 | 6 | UniProt (I0B503) Pfam (PF01048) | Schistosoma mansoni (Blood fluke) | 5'-methylthioadenosine phosphorylase |
| 2 | G, I, K, M, O... (A, B, C, D, E...) | '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL | non-polymer | 266.3 | 6 | Chemie (TBN) PubChem (17754195) PubChem (6245) PubChem (21776949) PubChem (23616027) PubChem (125133) PubChem (163051) PubChem (46233579) PubChem (46936593) PubChem (44330586) PubChem (3007918) PubChem (5604) PubChem (9943250) PubChem (92209902) PubChem (92209903) PubChem (92209904) PubChem (92846012) PubChem (12444557) PubChem (12444556) PubChem (135258248) PubChem (142417067) PubChem (162472531) PubChem (162472554) PubChem (162472564) PubChem (162472569) PubChem (162964384) PubChem (163608668) PubChem (171699467) PubChem (173772104) PubChem (173772143) PubChem (173979230) | |||
| 3 | H, J, L, N, P... (A, B, C, D, E...) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | S, T, U, V, W... (A, B, C, D, E...) | water | water | 18.0 | 561 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 299 (UniProt: I0B503)
| PDB | External Database | Details |
|---|---|---|
| Met -20 | - | expression tag |
| Gly -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Ser -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| Ser -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Val -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Arg -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 211556.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2173.9 | |
| All* | Total formula weight | 213730.8 |
