4L4S
Structural characterisation of the NADH binary complex of human lactate dehydrogenase M isozyme
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H, A | L-lactate dehydrogenase A chain | polymer | 339 | 37674.6 | 2 | UniProt (P00338) Pfam (PF00056) Pfam (PF02866) In PDB | Homo sapiens (human) | LDH-A, Cell proliferation-inducing gene 19 protein, LDH muscle subunit, LDH-M, Renal carcinoma antigen NY-REN-59 |
2 | H, A | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 2 | Chemie (NAI) | |||
3 | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence modifications
H, A: 1 - 331 (UniProt: P00338)
PDB | External Database | Details |
---|---|---|
Leu 332 | - | expression tag |
Glu 333 | - | expression tag |
His 334 | - | expression tag |
His 335 | - | expression tag |
His 336 | - | expression tag |
His 337 | - | expression tag |
His 338 | - | expression tag |
His 339 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 75349.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1330.9 | |
All* | Total formula weight | 76680.1 |