4L42
Crystal structures of human p70S6K1-PIF
エンティティ
Entity ID | 鎖名 | 説明 | 種類 | 鎖長 | 化学式量 | 分子数 | データベース名(アクセス番号) | 由来する生物種 | エンティティの一般名 |
1 | A | RPS6KB1 protein | polymer | 346 | 39372.3 | 1 | UniProt (Q7Z721) Pfam (PF00069) Pfam (PF00433) UniProt (by SIFTS) (P23443) In PDB | Homo sapiens (human) | Ribosomal protein S6 kinase beta-1, Ribosomal protein S6 kinase, 70kDa, polypeptide 1, isoform CRA_c |
2 | A | 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole | non-polymer | 390.4 | 1 | Chemie (5FI) | |||
3 | A | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
5 | water | water | 18.0 | 12 | Chemie (HOH) |
配列変更
A: 52 - 394 (UniProt: Q7Z721)
PDB | 外部データベース | 詳細 |
---|---|---|
Gly 49 | - | expression tag |
Ala 50 | - | expression tag |
Met 51 | - | expression tag |
Glu 380 | Ser 403 | engineered mutation |
Glu 381 | Ala 404 | engineered mutation |
Gln 382 | Asn 405 | engineered mutation |
Glu 383 | Gln 406 | engineered mutation |
Met 384 | Val 407 | engineered mutation |
Arg 386 | Leu 409 | engineered mutation |
Asp 387 | Gly 410 | engineered mutation |
Glu 389 | Thr 412 | engineered mutation |
Ile 391 | Val 414 | engineered mutation |
Asp 393 | Pro 416 | engineered mutation |
Trp 394 | Ser 417 | engineered mutation |
配列ビューア
非対称単位の内容
タンパク質・ 核酸鎖 | 鎖の数 | 1 |
化学式量合計 | 39372.3 | |
タンパク質・ 核酸・ 糖鎖以外* | 分子数 | 9 |
化学式量合計 | 1128.3 | |
全て* | 化学式量合計 | 40500.6 |