4L3J
Crystal structures of human p70S6K1 kinase domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RPS6KB1 protein | polymer | 304 | 34337.1 | 1 | UniProt (Q7Z721) Pfam (PF00069) UniProt (by SIFTS) (P23443) | Homo sapiens (human) | Ribosomal protein S6 kinase beta-1, Ribosomal protein S6 kinase, 70kDa, polypeptide 1, isoform CRA_c |
| 2 | B (A) | 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole | non-polymer | 390.4 | 1 | Chemie (5FI) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | water | water | 18.0 | 121 | Chemie (HOH) |
Sequence modifications
A: 52 - 352 (UniProt: Q7Z721)
| PDB | External Database | Details |
|---|---|---|
| Gly 49 | - | expression tag |
| Ala 50 | - | expression tag |
| Met 51 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34337.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 455.8 | |
| All* | Total formula weight | 34792.9 |
