4L28
Crystal structure of delta516-525 human cystathionine beta-synthase D444N mutant containing C-terminal 6xHis tag
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cystathionine beta-synthase | polymer | 558 | 61604.4 | 4 | UniProt (P35520) Pfam (PF00291) Pfam (PF00571) | Homo sapiens (human) | Beta-thionase, Serine sulfhydrase |
| 2 | E, G, I, K (A, B, C, D) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 4 | Chemie (PLP) | |||
| 3 | F, H, J, L (A, B, C, D) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) |
Sequence modifications
A, B, C, D: 2 - 551 (UniProt: P35520)
| PDB | External Database | Details |
|---|---|---|
| Asn 444 | Asp 444 | engineered mutation |
| Leu 552 | - | expression tag |
| Glu 553 | - | expression tag |
| His 554 | - | expression tag |
| His 555 | - | expression tag |
| His 556 | - | expression tag |
| His 557 | - | expression tag |
| His 558 | - | expression tag |
| His 559 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 246417.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3454.5 | |
| All* | Total formula weight | 249872.0 |
