4L1M

Structure of the first RCC1-like domain of HERC2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	E3 ubiquitin-protein ligase HERC2	polymer	392	42061.2	3	UniProt (O95714) Pfam (PF00415) In PDB	Homo sapiens (human)	HECT domain and RCC1-like domain-containing protein 2
2	A, C, B	SULFATE ION	non-polymer		96.1	11	Chemie (SO4)
3	B, A, C	UNKNOWN ATOM OR ION	non-polymer			34	Chemie (UNX)
4		water	water		18.0	51	Chemie (HOH)

Sequence modifications

A, B, C: 417 - 790 (UniProt: O95714)

PDB	External Database	Details
Met 399	-	expression tag
His 400	-	expression tag
His 401	-	expression tag
His 402	-	expression tag
His 403	-	expression tag
His 404	-	expression tag
His 405	-	expression tag
Ser 406	-	expression tag
Ser 407	-	expression tag
Gly 408	-	expression tag
Arg 409	-	expression tag
Glu 410	-	expression tag
Asn 411	-	expression tag
Leu 412	-	expression tag
Tyr 413	-	expression tag
Phe 414	-	expression tag
Gln 415	-	expression tag
Gly 416	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	126183.5
Non-Polymers*	Number of molecules	45
	Total formula weight	1056.7
All*	Total formula weight	127240.2

*Water molecules are not included.