4L1J
Three dimensional structure of mutant D143A of human HD domain-containing protein 2, Northeast Structural Genomics Consortium (NESG) Target HR6723
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HD domain-containing protein 2 | polymer | 204 | 23754.7 | 1 | UniProt (Q7Z4H3) Pfam (PF13023) | Homo sapiens (human) | Hepatitis C virus NS5A-transactivated protein 2, HCV NS5A-transactivated protein 2 |
| 2 | B (B) | HD domain-containing protein 2 (Phosphorylate) | polymer | 204 | 23834.7 | 1 | UniProt (Q7Z4H3) Pfam (PF13023) | Homo sapiens (human) | |
| 3 | C, D, E, F, G... (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 6 | Chemie (PEG) | |||
| 4 | I (B) | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL | non-polymer | 354.4 | 1 | Chemie (PE4) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 246 | Chemie (HOH) |
Sequence modifications
A: 1 - 204 (UniProt: Q7Z4H3)
B: 1 - 204 (UniProt: Q7Z4H3)
| PDB | External Database | Details |
|---|---|---|
| Ala 143 | Asp 143 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 143 | Asp 143 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47589.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 991.2 | |
| All* | Total formula weight | 48580.5 |
