4L18
Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 3)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Runt-related transcription factor 1 | polymer | 167 | 18741.3 | 2 | UniProt (Q03347) Pfam (PF00853) | Mus musculus (mouse) | Runx1, Acute myeloid leukemia 1 protein, Core-binding factor subunit alpha-2, CBF-alpha-2, Oncogene AML-1, Polyomavirus enhancer-binding protein 2 alpha B subunit, PEA2-alpha B, PEBP2-alpha B, SL3-3 enhancer factor 1 alpha B subunit, SL3/AKV core-binding factor alpha B subunit |
| 2 | B, F (B, F) | Protein C-ets-1 | polymer | 146 | 16973.4 | 2 | UniProt (P14921) Pfam (PF00178) | Homo sapiens (human) | Ets1, p54 |
| 3 | C, G (C, G) | 5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3' | polymer | 16 | 4843.2 | 2 | Homo sapiens | ||
| 4 | D, H (D, H) | 5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3' | polymer | 16 | 4954.2 | 2 | Homo sapiens | ||
| 5 | I (D) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | J, K, L, M, N... (A, B, C, D, E...) | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 91024.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 91116.3 |
