4L0Z
Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Runt-related transcription factor 1 | polymer | 242 | 26492.1 | 1 | UniProt (Q03347) Pfam (PF00853) | Mus musculus (mouse) | Runx1, Acute myeloid leukemia 1 protein, Core-binding factor subunit alpha-2, CBF-alpha-2, Oncogene AML-1, Polyomavirus enhancer-binding protein 2 alpha B subunit, PEA2-alpha B, PEBP2-alpha B, SL3-3 enhancer factor 1 alpha B subunit, SL3/AKV core-binding factor alpha B subunit |
| 2 | B (B) | Protein C-ets-1 | polymer | 146 | 16973.4 | 1 | UniProt (P14921) Pfam (PF00178) | Homo sapiens (human) | Ets1, p54 |
| 3 | C (C) | 5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3' | polymer | 16 | 4843.2 | 1 | Homo sapiens | ||
| 4 | D (D) | 5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3' | polymer | 16 | 4954.2 | 1 | Homo sapiens | ||
| 5 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A: 1 - 242 (UniProt: Q03347)
| PDB | External Database | Details |
|---|---|---|
| Ala 36 | Gly 36 | conflict |
| Ala 38 | Pro 38 | conflict |
| Gly 42 | Ser 42 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 53262.8 | |
| All* | Total formula weight | 53262.8 |
