4L0D
Crystal structure of delta516-525 human cystathionine beta-synthase containing C-terminal 6xHis-tag
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cystathionine beta-synthase | polymer | 549 | 60605.3 | 2 | UniProt (P35520) Pfam (PF00291) Pfam (PF00571) | Homo sapiens (human) | Beta-thionase, Serine sulfhydrase |
| 2 | C, E (A, B) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 2 | Chemie (PLP) | |||
| 3 | D, F (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) |
Sequence modifications
A, B: 1 - 551 (UniProt: P35520)
| PDB | External Database | Details |
|---|---|---|
| Gly 2 | Pro 2 | engineered mutation |
| - | Ile 516 | deletion |
| - | Gln 517 | deletion |
| - | Tyr 518 | deletion |
| - | His 519 | deletion |
| - | Ser 520 | deletion |
| - | Thr 521 | deletion |
| - | Gly 522 | deletion |
| - | Lys 523 | deletion |
| - | Ser 524 | deletion |
| - | Ser 525 | deletion |
| Glu 552 | - | expression tag |
| Leu 553 | - | expression tag |
| His 554 | - | expression tag |
| His 555 | - | expression tag |
| His 556 | - | expression tag |
| His 557 | - | expression tag |
| His 558 | - | expression tag |
| His 559 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 121210.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1727.3 | |
| All* | Total formula weight | 122937.9 |
