4KXX

Human transketolase in covalent complex with donor ketose D-sedoheptulose-7-phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Transketolase	polymer	637	69647.5	1	UniProt (P29401) Pfam (PF00456) Pfam (PF02779) Pfam (PF02780)	Homo sapiens (human)	TK
2	B (A)	(2R,3R,4S,5R,6S)-2,3,4,5,6,7-hexahydroxyheptyl dihydrogen phosphate	non-polymer		292.2	1	Chemie (1Y7)
3	C (A)	THIAMINE DIPHOSPHATE	non-polymer		425.3	1	Chemie (TPP)
4	D, E, F, G, H... (A)	1,2-ETHANEDIOL	non-polymer		62.1	12	Chemie (EDO)
5	N (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
6	P (A)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
7	R (A)	water	water		18.0	785	Chemie (HOH)

Sequence modifications

A: 1 - 623 (UniProt: P29401)

PDB	External Database	Details
Leu 624	-	expression tag
Val 625	-	expression tag
Pro 626	-	expression tag
Arg 627	-	expression tag
Gly 628	-	expression tag
Ser 629	-	expression tag
Leu 630	-	expression tag
Glu 631	-	expression tag
His 632	-	expression tag
His 633	-	expression tag
His 634	-	expression tag
His 635	-	expression tag
His 636	-	expression tag
His 637	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	69647.5
Non-Polymers*	Number of molecules	16
	Total formula weight	1509.6
All*	Total formula weight	71157.1

*Water molecules are not included.