4KXB
Crystal structure of human aminopeptidase A complexed with bestatin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Glutamyl aminopeptidase | polymer | 888 | 102719.5 | 1 | UniProt (Q07075) Pfam (PF17900) Pfam (PF01433) Pfam (PF11838) In PDB | Homo sapiens (human) | EAP, Aminopeptidase A, AP-A, Differentiation antigen gp160 |
2 | B, C, F, G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
3 | D, E | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 627.6 | 2 | In PDB BIRD (PRD_900017) GlyTouCan (G47362BJ) | triacetyl-beta-chitotriose | ||
4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
5 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
6 | A | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID | non-polymer | 308.4 | 1 | Chemie (BES) | |||
7 | water | water | 18.0 | 445 | Chemie (HOH) |
Sequence modifications
A: 76 - 957 (UniProt: Q07075)
PDB | External Database | Details |
---|---|---|
Arg 213 | Gln 213 | variant |
Ala 218 | Val 218 | variant |
His 958 | - | expression tag |
His 959 | - | expression tag |
His 960 | - | expression tag |
His 961 | - | expression tag |
His 962 | - | expression tag |
His 963 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 102719.5 | |
Branched | Number of molecules | 6 |
Total formula weight | 2952.8 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 595.0 | |
All* | Total formula weight | 106267.3 |