4KX3
Structure of murine cytosolic 5'-nucleotidase III complexed with thymidine monophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 1 of Cytosolic 5'-nucleotidase 3A | polymer | 297 | 33940.0 | 1 | UniProt (Q9D020) Pfam (PF05822) | Mus musculus (house mouse) | 7-methylguanosine phosphate-specific 5'-nucleotidase,7-methylguanosine nucleotidase,Cytosolic 5'-nucleotidase 3,Cytosolic 5'-nucleotidase III,cN-III,Lupin,Pyrimidine 5'-nucleotidase 1,P5'N-1,P5N-1,PN-I |
| 2 | B (A) | THYMIDINE-5'-PHOSPHATE | non-polymer | 322.2 | 1 | Chemie (TMP) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D, E, F, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | G (A) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 6 | I (A) | water | water | 18.0 | 246 | Chemie (HOH) |
Sequence modifications
A: 1 - 297 (UniProt: Q9D020)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | Met 1 | engineered mutation |
| Asn 51 | Asp 51 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33940.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 833.1 | |
| All* | Total formula weight | 34773.1 |
