4KWI

The crystal structure of angucycline C-6 ketoreductase LanV with bound NADP and 11-deoxy-6-oxylandomycinone

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Reductase homolog	polymer	263	27501.1	2	UniProt (Q9ZGC1) Pfam (PF13561) In PDB	Streptomyces cyanogenus
2	A, B	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	2	Chemie (NAP)
3	A, B	1,8-dihydroxy-3-methyltetraphene-6,7,12(5H)-trione	non-polymer		320.3	2	Chemie (1TJ)
4	A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
5		water	water		18.0	239	Chemie (HOH)

Sequence modifications

A, B: 2 - 253 (UniProt: Q9ZGC1)

PDB	External Database	Details
Met -9	-	initiating methionine
Ala -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
Arg 0	-	expression tag
Ser 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	55002.1
Non-Polymers*	Number of molecules	5
	Total formula weight	2233.5
All*	Total formula weight	57235.7

*Water molecules are not included.