4KWI
The crystal structure of angucycline C-6 ketoreductase LanV with bound NADP and 11-deoxy-6-oxylandomycinone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Reductase homolog | polymer | 263 | 27501.1 | 2 | UniProt (Q9ZGC1) Pfam (PF13561) | Streptomyces cyanogenus | |
| 2 | C, F (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | D, G (A, B) | 1,8-dihydroxy-3-methyltetraphene-6,7,12(5H)-trione | non-polymer | 320.3 | 2 | Chemie (1TJ) | |||
| 4 | E (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 239 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 253 (UniProt: Q9ZGC1)
| PDB | External Database | Details |
|---|---|---|
| Met -9 | - | initiating methionine |
| Ala -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| Arg 0 | - | expression tag |
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55002.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2233.5 | |
| All* | Total formula weight | 57235.7 |
