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4KVP

Human p53 Core Domain Mutant V157F

Replaces:  2QXA
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Cellular tumor antigen p53polymer22024706.04UniProt (P04637)
Pfam (PF00870)
Homo sapiens (human)Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53
2E, F, G, H
(A, B, C, D)
ZINC IONnon-polymer65.44Chemie (ZN)
3I, J, K, L
(A, B, C, D)
waterwater18.01035Chemie (HOH)
Sequence modifications
A, B, C, D: 94 - 312 (UniProt: P04637)
PDBExternal DatabaseDetails
Ala 93-expression tag
Phe 157Val 157engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight98824.0
Non-Polymers*Number of molecules4
Total formula weight261.6
All*Total formula weight99085.6
*Water molecules are not included.

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PDB entries from 2025-12-24

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