4KUD

Crystal structure of N-terminal acetylated Sir3 BAH domain D205N mutant in complex with yeast nucleosome core particle

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	Histone H3	polymer	136	15391.0	2	UniProt (P61830) Pfam (PF00125)	Saccharomyces cerevisiae (yeast)
2	B, F (B, F)	Histone H4	polymer	103	11395.4	2	UniProt (P02309) Pfam (PF15511)	Saccharomyces cerevisiae (yeast)
3	C, G (C, G)	Histone H2A.2	polymer	132	13997.2	2	UniProt (P04912) Pfam (PF00125) Pfam (PF16211)	Saccharomyces cerevisiae (yeast)
4	D, H (D, H)	Histone H2B.1	polymer	131	14280.4	2	UniProt (P02293) Pfam (PF00125)	Saccharomyces cerevisiae (yeast)	Suppressor of Ty protein 12
5	I, J (I, J)	nucloesome DNA	polymer	146	45054.8	2
6	K, L (K, L)	Regulatory protein SIR3	polymer	224	26773.3	2	UniProt (P06701) Pfam (PF01426)	Saccharomyces cerevisiae (yeast)	Silent information regulator 3
7	M, N, O, P, Q... (A, B, C, D, E...)	water	water		18.0	66	Chemie (HOH)

Sequence modifications

C, G: 0 - 131 (UniProt: P04912)

PDB	External Database	Details
Ala 1	Ser 2	engineered mutation

K, L: 2 - 219 (UniProt: P06701)

PDB	External Database	Details
Asn 205	Asp 205	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	253784.2
All*	Total formula weight	253784.2

*Water molecules are not included.