4KTT
Structural insights of MAT enzymes: MATa2b complexed with SAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | S-adenosylmethionine synthase isoform type-2 | polymer | 396 | 43807.7 | 4 | UniProt (P31153) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773) | Homo sapiens (human) | AdoMet synthase 2, Methionine adenosyltransferase 2, MAT 2, Methionine adenosyltransferase II, MAT-II |
| 2 | E, F (E, F) | Methionine adenosyltransferase 2 subunit beta | polymer | 327 | 36862.8 | 2 | UniProt (Q9NZL9) Pfam (PF04321) | Homo sapiens (human) | Methionine adenosyltransferase II beta, MAT II beta, Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase |
| 3 | BA, CA, DA, EA, FA... (D, A, E, B, F...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 28 | Chemie (EDO) | |||
| 4 | K, Z (A, C) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) | |||
| 5 | AA, L (C, A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 6 | V (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | NA, OA, PA, QA, RA... (A, B, C, D, E...) | water | water | 18.0 | 108 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 395 (UniProt: P31153)
E, F: 9 - 323 (UniProt: Q9NZL9)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 248956.5 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 2749.0 | |
| All* | Total formula weight | 251705.5 |
