4KT8
The complex structure of Rv3378c-Y51FY90F with substrate, TPP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Diterpene synthase | polymer | 296 | 34039.5 | 1 | UniProt (O50407) UniProt (by SIFTS) (P9WJ61) In PDB | Mycobacterium tuberculosis | Isotuberculosinol synthase, Nosyberkol synthase, Tuberculosinol synthase |
| 2 | A | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 3 | A | (2E)-3-methyl-5-[(1R,2S,8aS)-1,2,5,5-tetramethyl-1,2,3,5,6,7,8,8a-octahydronaphthalen-1-yl]pent-2-en-1-yl trihydrogen diphosphate | non-polymer | 450.4 | 1 | Chemie (9AX) | |||
| 4 | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A: 1 - 296 (UniProt: O50407)
| PDB | External Database | Details |
|---|---|---|
| Phe 51 | Tyr 51 | engineered mutation |
| Phe 90 | Tyr 90 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34039.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 735.4 | |
| All* | Total formula weight | 34774.8 |
