4KS8
PAK6 kinase domain in complex with sunitinib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase PAK 6 | polymer | 292 | 33301.6 | 1 | UniProt (Q9NQU5) Pfam (PF00069) | Homo sapiens (human) | PAK-5, p21-activated kinase 6, PAK-6 |
| 2 | B (A) | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide | non-polymer | 398.5 | 1 | Chemie (B49) | |||
| 3 | C (A) | water | water | 18.0 | 171 | Chemie (HOH) |
Sequence modifications
A: 385 - 674 (UniProt: Q9NQU5)
| PDB | External Database | Details |
|---|---|---|
| Gly 383 | - | expression tag |
| Ser 384 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33301.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 398.5 | |
| All* | Total formula weight | 33700.0 |
