4KQE
The mutant structure of the human glycyl-tRNA synthetase E71G
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glycine--tRNA ligase | polymer | 693 | 78632.8 | 1 | UniProt (P41250) Pfam (PF00458) Pfam (PF00587) Pfam (PF03129) | Homo sapiens (human) | Glycyl-tRNA synthetase, Diadenosine tetraphosphate synthetase, AP-4-A synthetase, GlyRS |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (A) | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A: 1 - 685 (UniProt: P41250)
| PDB | External Database | Details |
|---|---|---|
| Gly 71 | Glu 125 | engineered mutation |
| Leu 686 | - | expression tag |
| Glu 687 | - | expression tag |
| His 688 | - | expression tag |
| His 689 | - | expression tag |
| His 690 | - | expression tag |
| His 691 | - | expression tag |
| His 692 | - | expression tag |
| His 693 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 78632.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 78724.9 |
