4KNM
Crystal structure of human carbonic anhydrase isozyme XIII with 2-Chloro-4-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Carbonic anhydrase 13 | polymer | 263 | 29613.3 | 2 | UniProt (Q8N1Q1) Pfam (PF00194) | Homo sapiens (human) | Carbonate dehydratase XIII, Carbonic anhydrase XIII, CA-XIII |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G (A, B) | 2-chloro-4-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide | non-polymer | 371.9 | 2 | Chemie (E1E) | |||
| 4 | E (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 338 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 263 (UniProt: Q8N1Q1)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59226.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1024.7 | |
| All* | Total formula weight | 60251.4 |
