4KMU

X-ray crystal structure of the Escherichia coli RNA polymerase in complex with Rifampin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, G, H (A, B, F, G)	DNA-directed RNA polymerase subunit alpha	polymer	329	36558.7	4	UniProt (P0A7Z4) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118)	Escherichia coli	RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha
2	C, I (C, H)	DNA-directed RNA polymerase subunit beta	polymer	1342	150820.9	2	UniProt (P0A8V2) Pfam (PF04560) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562)	Escherichia coli	RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta
3	D, J (D, I)	DNA-directed RNA polymerase subunit beta'	polymer	1407	155366.8	2	UniProt (P0A8T7) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998)	Escherichia coli	RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'
4	E, K (E, J)	DNA-directed RNA polymerase subunit omega	polymer	91	10249.5	2	UniProt (P0A800) Pfam (PF01192)	Escherichia coli	RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega
5	F, L (X, Y)	RNA polymerase sigma factor RpoD	polymer	613	70352.2	2	UniProt (P00579) Pfam (PF03979) Pfam (PF00140) Pfam (PF04546) Pfam (PF04542) Pfam (PF04539) Pfam (PF04545)	Escherichia coli	Sigma-70
6	M, Q (C, H)	RIFAMPICIN	non-polymer		822.9	2	Chemie (RFP)
7	N, O, R, S (D, I)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
8	P, T (D, I)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	919813.6
Non-Polymers*	Number of molecules	8
	Total formula weight	1956.1
All*	Total formula weight	921769.7

*Water molecules are not included.