4KMM
M76H variant of human ferrochelatase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Ferrochelatase, mitochondrial | polymer | 370 | 42403.6 | 2 | UniProt (P22830) Pfam (PF00762) In PDB | Homo sapiens (human) | Heme synthase, Protoheme ferro-lyase |
2 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
3 | A, B | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
4 | A, B | CHOLIC ACID | non-polymer | 408.6 | 4 | Chemie (CHD) | |||
5 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
6 | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
A, B: 65 - 423 (UniProt: P22830)
PDB | External Database | Details |
---|---|---|
Met 54 | - | expression tag |
Gly 55 | - | expression tag |
Gly 56 | - | expression tag |
Ser 57 | - | expression tag |
His 58 | - | expression tag |
His 59 | - | expression tag |
His 60 | - | expression tag |
His 61 | - | expression tag |
His 62 | - | expression tag |
His 63 | - | expression tag |
Gly 64 | - | expression tag |
His 76 | Met 76 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 84807.3 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 3289.8 | |
All* | Total formula weight | 88097.1 |