4KML
Probing the N-terminal beta-sheet conversion in the crystal structure of the full-length human prion protein bound to a Nanobody
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Major prion protein | polymer | 241 | 26201.9 | 1 | UniProt (P04156) Pfam (PF00377) In PDB | Homo sapiens (human) | PrP, ASCR, PrP27-30, PrP33-35C |
2 | B | Nanobody | polymer | 130 | 14276.8 | 1 | Lama glama (llama) | ||
3 | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
A: 24 - 231 (UniProt: P04156)
PDB | External Database | Details |
---|---|---|
Met -9 | - | expression tag |
Gly -8 | - | expression tag |
Ser -7 | - | expression tag |
Ser -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Ser 1 | - | expression tag |
Ser 2 | - | expression tag |
Gly 3 | - | expression tag |
Leu 4 | - | expression tag |
Val 5 | - | expression tag |
Pro 6 | - | expression tag |
Arg 7 | - | expression tag |
Gly 8 | - | expression tag |
Ser 9 | - | expression tag |
His 10 | - | expression tag |
Met 11 | - | expression tag |
Ala 12 | - | expression tag |
Ser 13 | - | expression tag |
Met 14 | - | expression tag |
Thr 15 | - | expression tag |
Gly 16 | - | expression tag |
Gly 17 | - | expression tag |
Gln 18 | - | expression tag |
Gln 19 | - | expression tag |
Met 20 | - | expression tag |
Gly 21 | - | expression tag |
Arg 22 | - | expression tag |
Gly 23 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 40478.7 | |
All* | Total formula weight | 40478.7 |