4KKX
Crystal structure of Tryptophan Synthase from Salmonella typhimurium with 2-aminophenol quinonoid in the beta site and the F6 inhibitor in the alpha site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tryptophan synthase alpha chain | polymer | 268 | 28698.8 | 1 | UniProt (P00929) Pfam (PF00290) | Salmonella enterica subsp. enterica serovar Typhimurium | |
| 2 | B (B) | Tryptophan synthase beta chain | polymer | 397 | 42918.9 | 1 | UniProt (P0A2K1) Pfam (PF00291) | Salmonella enterica subsp. enterica serovar Typhimurium | |
| 3 | C (A) | 2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL DIHYDROGEN PHOSPHATE | non-polymer | 329.2 | 1 | Chemie (F6F) | |||
| 4 | D, I, J (A, B) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 5 | E, K, L, M, N... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
| 6 | F, G (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 7 | H (B) | N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-3-[(2-hydroxyphenyl)amino]-D-alanine | non-polymer | 427.3 | 1 | Chemie (AQ3) | |||
| 8 | T, U (B) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 9 | V, W (A, B) | water | water | 18.0 | 928 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71617.7 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 1958.7 | |
| All* | Total formula weight | 73576.4 |
