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4KK8

Structure of the E148Q mutant of CLC-ec1 deltaNC construct in 100mM fluoride

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
H(+)/Cl(-) exchange transporter ClcApolymer44647617.42UniProt (P37019)
Pfam (PF00654)
Escherichia coliClC-ec1
2C, E
(C, E)
Fab, heavy chainpolymer22223823.02Mus musculus
3D, F
(D, F)
Fab, light chainpolymer21123088.42Pfam (PF07654)
UniProt (by SIFTS) (P01837)
Mus musculus
4G, H
(A, B)
FLUORIDE IONnon-polymer19.02Chemie (F)
Sequence modifications
A, B: 17 - 460 (UniProt: P37019)
PDBExternal DatabaseDetails
Met 16-expression tag
Gln 148Glu 148engineered mutation
Lys 461-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight189057.8
Non-Polymers*Number of molecules2
Total formula weight38.0
All*Total formula weight189095.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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