4KIG

Crystal structure of methyltransferase from Streptomyces hygroscopicus complexed with 4-hydroxyphenylpyruvic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Methyltransferase MppJ	polymer	357	39400.3	2	UniProt (Q643C8) Pfam (PF13649)	Streptomyces hygroscopicus
2	C, K (A, B)	3-(4-HYDROXY-PHENYL)PYRUVIC ACID	non-polymer		180.2	2	Chemie (ENO)
3	D, L (A, B)	FE (III) ION	non-polymer		55.8	2	Chemie (FE)
4	E, M (A, B)	(2R)-2-HYDROXY-3-(4-HYDROXYPHENYL)PROPANOIC ACID	non-polymer		182.2	2	Chemie (34H)
5	F, G, H, I, J... (A, B)	CALCIUM ION	non-polymer		40.1	9	Chemie (CA)
6	R, S (A, B)	water	water		18.0	358	Chemie (HOH)

Sequence modifications

A, B: 1 - 337 (UniProt: Q643C8)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	78800.6
Non-Polymers*	Number of molecules	15
	Total formula weight	1197.1
All*	Total formula weight	79997.6

*Water molecules are not included.