4KI1
Primitive triclinic crystal form of the human IgE-Fc(epsilon)3-4 bound to its B cell receptor derCD23
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | IG EPSILON CHAIN C REGION | polymer | 223 | 24920.1 | 4 | UniProt (P01854) Pfam (PF07654) | Homo sapiens (human) | |
| 2 | E, F, G, H (E, F, G, H) | LOW AFFINITY IMMUNOGLOBULIN EPSILON FC RECEPTOR | polymer | 143 | 16165.0 | 4 | UniProt (P06734) Pfam (PF00059) | Homo sapiens (human) | BLAST-2, C-type lectin domain family 4 member J, Fc-epsilon-RII, Immunoglobulin E-binding factor, Lymphocyte IgE receptor, Low affinity immunoglobulin epsilon Fc receptor membrane-bound form, Low affinity immunoglobulin epsilon Fc receptor soluble form |
| 3 | I, J, K, L (I, J, K, L) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 4 | In PDB GlyTouCan (G22768VO) | |||
| 4 | M, N (B, D) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 328 - 547 (UniProt: P01854)
| PDB | External Database | Details |
|---|---|---|
| Ala 325 | - | expression tag |
| Asp 326 | - | expression tag |
| Pro 327 | - | expression tag |
| Gln 371 | Asn 252 | engineered mutation |
| Gln 383 | Asn 264 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 164340.5 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 3643.3 | |
| All* | Total formula weight | 167983.8 |
