4KFQ
Crystal structure of the NMDA receptor GluN1 ligand binding domain in complex with 1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamate receptor ionotropic, NMDA 1 | polymer | 292 | 33340.0 | 2 | UniProt (P35439) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (brown rat rat rats) | GluN1, Glutamate [NMDA] receptor subunit zeta-1, N-methyl-D-aspartate receptor subunit NR1, NMD-R1 |
| 2 | C, Q (A, B) | 1-sulfanyl[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one | non-polymer | 218.2 | 2 | Chemie (KFQ) | |||
| 3 | D, E, F, G, H... (A, B) | GLYCEROL | non-polymer | 92.1 | 18 | Chemie (GOL) | |||
| 4 | AA, BA, CA, DA, M... (B, A) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 5 | EA, FA (A, B) | water | water | 18.0 | 414 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 152 (UniProt: P35439)
A, B: 155 - 292 (UniProt: P35439)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 153 | - | linker |
| Thr 154 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66680.1 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 2862.7 | |
| All* | Total formula weight | 69542.7 |
