4KDT
Structure of an early native-like intermediate of beta2-microglobulin amyloidosis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Nanobody24 | polymer | 134 | 14991.5 | 2 | Camelidae | ||
| 2 | C, D | Beta-2-microglobulin | polymer | 100 | 11839.3 | 2 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
| 3 | A, B, C, D | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | C, D | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 50 | Chemie (HOH) |
Sequence modifications
C, D: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Gly 32 | Pro 52 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 53661.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 760.6 | |
| All* | Total formula weight | 54422.1 |
