4KDI

Crystal structure of p97/VCP N in complex with OTU1 UBXL

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transitional endoplasmic reticulum ATPase	polymer	193	21806.0	2	UniProt (P55072) Pfam (PF02359) Pfam (PF02933)	Homo sapiens (human)	TER ATPase, 15S Mg(2+)-ATPase p97 subunit, Valosin-containing protein, VCP
2	C, D (C, D)	Ubiquitin thioesterase OTU1	polymer	90	9694.0	2	UniProt (P43558) Pfam (PF21403)	Saccharomyces cerevisiae (Baker's yeast)	OTU domain-containing protein 1
3	E, F, G, H (A, B, C, D)	water	water		18.0	198	Chemie (HOH)

Sequence modifications

A, B: 21 - 196 (UniProt: P55072)

PDB	External Database	Details
Gly 4	-	expression tag
Ser 5	-	expression tag
His 6	-	expression tag
Met 7	-	expression tag
Ala 8	-	expression tag
Ser 9	-	expression tag
Met 10	-	expression tag
Thr 11	-	expression tag
Gly 12	-	expression tag
Gly 13	-	expression tag
Gln 14	-	expression tag
Gln 15	-	expression tag
Met 16	-	expression tag
Gly 17	-	expression tag
Arg 18	-	expression tag
Gly 19	-	expression tag
Ser 20	-	expression tag

C, D: 1 - 73 (UniProt: P43558)

PDB	External Database	Details
Gly -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
Met -13	-	expression tag
Ala -12	-	expression tag
Ser -11	-	expression tag
Met -10	-	expression tag
Thr -9	-	expression tag
Gly -8	-	expression tag
Gly -7	-	expression tag
Gln -6	-	expression tag
Gln -5	-	expression tag
Met -4	-	expression tag
Gly -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	63000.0
All*	Total formula weight	63000.0

*Water molecules are not included.