4KAP
The Binding of Benzoarylsulfonamide Ligands to Human Carbonic Anhydrase is Insensitive to Formal Fluorination of the Ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbonic anhydrase 2 | polymer | 258 | 28979.7 | 1 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (human) | Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | 4,5,6,7-tetrafluoro-1,3-benzothiazole-2-sulfonamide | non-polymer | 286.2 | 1 | Chemie (1QV) | |||
| 4 | D (A) | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A: 5 - 261 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Ala 3 | - | expression tag |
| Asn 4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28979.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 351.6 | |
| All* | Total formula weight | 29331.3 |
