4KAB
FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 3-Methyl-1,4-dihydro-pyrazolo[4,5-c]pyrazole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Focal adhesion kinase 1 | polymer | 279 | 31957.9 | 2 | UniProt (Q05397) Pfam (PF07714) In PDB | Homo sapiens (human) | FADK 1, Focal adhesion kinase-related nonkinase, FRNK, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK, pp125FAK |
| 2 | A, B | 3-methyl-1,5-dihydropyrazolo[4,3-c]pyrazole | non-polymer | 122.1 | 2 | Chemie (4KA) | |||
| 3 | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
A, B: 410 - 686 (UniProt: Q05397)
| PDB | External Database | Details |
|---|---|---|
| Gly 408 | - | EXPRESSION TAG |
| Ser 409 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63915.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 244.3 | |
| All* | Total formula weight | 64160.1 |
