4K8O

CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF TAP1 WITH ATP (D645N, D651A MUTANT)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Antigen peptide transporter 1	polymer	271	29438.4	1	UniProt (P36370) Pfam (PF00005) In PDB	Rattus norvegicus (brown rat rat rats)	APT1, ATP-binding cassette sub-family B member 2, Peptide transporter TAP1
2	A	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	1	Chemie (ATP)
3	A	NICKEL (II) ION	non-polymer		58.7	1	Chemie (NI)
4	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	A	CITRIC ACID	non-polymer		192.1	1	Chemie (CIT)
6		water	water		18.0	20	Chemie (HOH)

Sequence modifications

A: 465 - 725 (UniProt: P36370)

PDB	External Database	Details
Met 464	-	EXPRESSION TAG
Asn 645	Asp 645	ENGINEERED MUTATION
Ala 651	Asp 651	ENGINEERED MUTATION
Ala 726	-	EXPRESSION TAG
Ala 727	-	EXPRESSION TAG
Ala 728	-	EXPRESSION TAG
His 729	-	EXPRESSION TAG
His 730	-	EXPRESSION TAG
His 731	-	EXPRESSION TAG
His 732	-	EXPRESSION TAG
His 733	-	EXPRESSION TAG
His 734	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29438.4
Non-Polymers*	Number of molecules	4
	Total formula weight	782.3
All*	Total formula weight	30220.7

*Water molecules are not included.