4K6W
Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0408
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Fiber protein | polymer | 194 | 21716.5 | 3 | UniProt (Q64823) Pfam (PF00541) | Human adenovirus 37 | |
| 2 | D, J, N (A, B, C) | 3,5-dideoxy-5-(propanoylamino)-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid | non-polymer | 323.3 | 3 | Chemie (18D) | |||
| 3 | E (A) | 2,2',2''-[nitrilotris(methanediyl-1H-1,2,3-triazole-4,1-diyl)]triethanol | non-polymer | 392.4 | 1 | Chemie (1P0) | |||
| 4 | F, K, O, P, Q (A, B, C) | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
| 5 | G, L, R (A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 6 | H, M, S (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 7 | I, T (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 8 | U, V, W (A, B, C) | water | water | 18.0 | 643 | Chemie (HOH) |
Sequence modifications
A, B, C: 177 - 365 (UniProt: Q64823)
| PDB | External Database | Details |
|---|---|---|
| Gly 172 | - | expression tag |
| Ala 173 | - | expression tag |
| Met 174 | - | expression tag |
| Gly 175 | - | expression tag |
| Ser 176 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 65149.6 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2088.6 | |
| All* | Total formula weight | 67238.2 |
