4K67
Structure of an airborne transmissible avian influenza H5 hemagglutinin mutant from the influenza virus A/Indonesia/5/2005 complexed with human receptor analog LSTc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Hemagglutinin | polymer | 321 | 36204.0 | 4 | UniProt (A8HWY8) | Influenza A virus | |
| 2 | B, D, F, H (B, D, F, H) | Hemagglutinin | polymer | 164 | 18910.8 | 4 | UniProt (A8HWY8) | Influenza A virus | |
| 3 | I, J (I, J) | N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose | branched | 471.4 | 2 | In PDB GlyTouCan (G63069TR) | |||
| 4 | K, L (K, L) | N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 674.6 | 2 | In PDB BIRD (PRD_900046) GlyTouCan (G73578JC) | 6'-sialyl-N-acetyllactosamine | ||
| 5 | M, N, O, P (A, C, E, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
A, C, E, G: 5 - 324 (UniProt: A8HWY8)
| PDB | External Database | Details |
|---|---|---|
| Gln 4 | - | expression tag |
| Tyr 107 | His 119 | engineered mutation |
| Ala 160 | Thr 172 | engineered mutation |
| Leu 226 | Gln 238 | engineered mutation |
| Ser 228 | Gly 240 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 220459.2 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2292.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 223636.0 |
