4K1I

Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Neuraminidase	polymer	388	43054.8	2	UniProt (Q194T1)	Influenza A virus
2	C, D (C, D)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	2	In PDB GlyTouCan (G81315DD)
3	E, H (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA) PubChem (271)
4	F, I (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
5	G, J (A, B)	(3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid	non-polymer		284.4	2	Chemie (G39) PubChem (40640967) PubChem (40640969) PubChem (40640971) PubChem (44345914) PubChem (40640973) PubChem (449381) PubChem (58753598) PubChem (4631786) PubChem (71038155) PubChem (71065667) PubChem (95162772) PubChem (121452907) PubChem (124637832) PubChem (129886749) PubChem (134694948) PubChem (137378365)
6	K, L (A, B)	water	water		18.0	933	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	86109.5
Branched	Number of molecules	2
	Total formula weight	1497.4
Non-Polymers*	Number of molecules	6
	Total formula weight	1091.3
All*	Total formula weight	88698.2

*Water molecules are not included.