4K1B
Structure of PIM-1 kinase bound to N-(5-(2-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-((((3R,4R)-3-fluoropiperidin-4-yl)methyl)amino)pyrazolo[1,5-a]pyrimidine-3-carboxamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase pim-1 | polymer | 273 | 31517.8 | 1 | UniProt (P11309) Pfam (PF00069) In PDB | Homo sapiens (human) | PIM-1 kinase |
| 2 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | A | N-[5-(2-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-5-({[(3R,4R)-3-fluoropiperidin-4-yl]methyl}amino)pyrazolo[1,5-a]pyrimidine-3-carboxamide | non-polymer | 502.5 | 1 | Chemie (1OC) | |||
| 4 | water | water | 18.0 | 127 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31517.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 597.5 | |
| All* | Total formula weight | 32115.3 |
