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4K18

Structure of PIM-1 kinase bound to 5-(4-cyanobenzyl)-N-(4-fluorophenyl)-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ASerine/threonine-protein kinase pim-1polymer27731934.21UniProt (P11309)
Pfam (PF00069)
In PDB
Homo sapiens (human)PIM-1 kinase
2APHOSPHATE IONnon-polymer95.01Chemie (PO4)
3A5-(4-cyanobenzyl)-N-(4-fluorophenyl)-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxamidenon-polymer387.41Chemie (1OB)
4waterwater18.0144Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight31934.2
Non-Polymers*Number of molecules2
Total formula weight482.3
All*Total formula weight32416.6
*Water molecules are not included.

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