4K11
The structure of 1NA in complex with Src T338G
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene tyrosine-protein kinase Src | polymer | 448 | 51207.9 | 1 | UniProt (P12931) Pfam (PF00018) Pfam (PF00017) Pfam (PF07714) | Homo sapiens (human) | c-Src tyrosine kinase, Proto-oncogene c-Src, pp60c-src, p60-Src |
| 2 | B (A) | 1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | non-polymer | 317.4 | 1 | Chemie (0J9) | |||
| 3 | C (A) | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
A: 84 - 531 (UniProt: P12931)
| PDB | External Database | Details |
|---|---|---|
| Gly 338 | Thr 341 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 51207.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 317.4 | |
| All* | Total formula weight | 51525.3 |
