4JZB
Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)-3-PHENYLPYRIDINIUM, IPP and Ca2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Farnesyl pyrophosphate synthase | polymer | 362 | 41045.2 | 2 | UniProt (Q4QBL1) Pfam (PF00348) | Leishmania major | |
| 2 | C, D, E, K, L... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 3 | F, I (A, B) | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE | non-polymer | 246.1 | 2 | Chemie (IPE) | |||
| 4 | G, J (A, B) | 1-(2-hydroxy-2,2-diphosphonoethyl)-3-phenylpyridinium | non-polymer | 360.2 | 2 | Chemie (P2H) | |||
| 5 | H, N (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 6 | O, P (A, B) | water | water | 18.0 | 696 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 362 (UniProt: Q4QBL1)
| PDB | External Database | Details |
|---|---|---|
| Fme 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82090.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1499.1 | |
| All* | Total formula weight | 83589.5 |
