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4JZB

Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)-3-PHENYLPYRIDINIUM, IPP and Ca2+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BFarnesyl pyrophosphate synthasepolymer36241045.22UniProt (Q4QBL1)
Pfam (PF00348)
In PDB
Leishmania major
2A, BCALCIUM IONnon-polymer40.16Chemie (CA)
3A, B3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATEnon-polymer246.12Chemie (IPE)
4A, B1-(2-hydroxy-2,2-diphosphonoethyl)-3-phenylpyridiniumnon-polymer360.22Chemie (P2H)
5A, BSODIUM IONnon-polymer23.02Chemie (NA)
6waterwater18.0696Chemie (HOH)
Sequence modifications
A, B: 2 - 362 (UniProt: Q4QBL1)
PDBExternal DatabaseDetails
Fme 1-EXPRESSION TAG
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight82090.4
Non-Polymers*Number of molecules12
Total formula weight1499.1
All*Total formula weight83589.5
*Water molecules are not included.

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PDB entries from 2024-06-12

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