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4JY4

Crystal structure of human Fab PGT121, a broadly reactive and potent HIV-1 neutralizing antibody

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
PGT121 heavy chainpolymer23525169.21Homo sapiens (human)
2B
(A)
PGT121 light chainpolymer21122574.91Homo sapiens (human)
3C
(C)
N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranosebranched1713.61In PDB
GlyTouCan (G84852GW)
4D, E, F
(B, A)
GLYCEROLnon-polymer92.13Chemie (GOL)
5G, H
(B, A)
waterwater18.013Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight47744.2
BranchedNumber of molecules1
Total formula weight1713.6
Non-Polymers*Number of molecules3
Total formula weight276.3
All*Total formula weight49734.0
*Water molecules are not included.

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PDB entries from 2025-12-24

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