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4JWN

Ternary complex of D256A mutant of DNA Polymerase Beta

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer33538197.71UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (human)
2B
(T)
DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')polymer164853.21
3C
(P)
DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3')polymer103061.01
4D
(D)
DNA (5'-D(P*GP*TP*CP*GP*G)-3')polymer51536.01
5E
(A)
2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATEnon-polymer467.21Chemie (DUP)
6F
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
7G, H
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
8I, J, K, L
(A)
CHLORIDE IONnon-polymer35.54Chemie (CL)
9M, N, O, P
(A, T, P, D)
waterwater18.0201Chemie (HOH)
Sequence modifications
A: 1 - 335 (UniProt: P06746)
PDBExternal DatabaseDetails
Ala 256Asp 256engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47647.9
Non-Polymers*Number of molecules8
Total formula weight679.3
All*Total formula weight48327.1
*Water molecules are not included.

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PDB entries from 2025-06-11

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