4JUH
Crystal structure of 1918 pandemic influenza virus hemagglutinin mutant D225G complexed with avian receptor analogue LSTa
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Hemagglutinin | polymer | 324 | 35710.1 | 3 | UniProt (Q9WFX3) Pfam (PF00509) | Influenza A virus | |
| 2 | B, D, F (B, D, F) | Hemagglutinin | polymer | 170 | 19450.5 | 3 | UniProt (Q9WFX3) Pfam (PF00509) | Influenza A virus | |
| 3 | G, I, J (G, I, J) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 4 | H (H) | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 674.6 | 1 | In PDB BIRD (PRD_900067) GlyTouCan (G00065MO) | 3'-sialyl-N-acetyllactosamine | ||
| 5 | K, L, M, N, O... (A, B, C, D, E...) | water | water | 18.0 | 199 | Chemie (HOH) |
Sequence modifications
A, C, E: 5 - 325 (UniProt: Q9WFX3)
| PDB | External Database | Details |
|---|---|---|
| Gly 225 | Asp 239 | engineered mutation |
| Ala 326 | - | expression tag |
| Arg 327 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 165481.6 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1947.8 | |
| All* | Total formula weight | 167429.4 |
