4JU0
Crystal structure of 2009 pandemic influenza virus hemagglutinin mutant D225E complexed with human receptor analogue LSTc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... (A, C, E, G, I...) | Hemagglutinin | polymer | 322 | 35830.5 | 6 | UniProt (C3W5S1) Pfam (PF00509) | Influenza A virus | |
| 2 | B, D, F, H, J... (B, D, F, H, J...) | Hemagglutinin | polymer | 164 | 18776.8 | 6 | UniProt (C3W5S1) | Influenza A virus | |
| 3 | M, N, P, Q, R (M, N, P, Q, R) | N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose | branched | 836.7 | 5 | In PDB GlyTouCan (G03509EL) | |||
| 4 | O (O) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | S, T, U, V, W... (C, G, I, K) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 6 | Y (K) | N-acetyl-alpha-neuraminic acid | non-polymer | 309.3 | 1 | Chemie (SIA) | |||
| 7 | AA, BA, CA, DA, EA... (B, C, D, E, F...) | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A, C, E, G, I, K: 7 - 328 (UniProt: C3W5S1)
| PDB | External Database | Details |
|---|---|---|
| Glu 228 | Asp 239 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 327643.3 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 4608.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1636.5 | |
| All* | Total formula weight | 333887.9 |
