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4JSX

structure of mTORDeltaN-mLST8-Torin2 complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(B, A)
Serine/threonine-protein kinase mTORpolymer1174134650.32UniProt (P42345)
Pfam (PF02259)
Pfam (PF08771)
Pfam (PF00454)
Pfam (PF02260)
Homo sapiens (human)FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, mTOR, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1
2B, D
(D, C)
Target of rapamycin complex subunit LST8polymer32635910.12UniProt (Q9BVC4)
Pfam (PF00400)
Homo sapiens (human)TORC subunit LST8, G protein beta subunit-like, Gable, Protein GbetaL, Mammalian lethal with SEC13 protein 8, mLST8
3E, F
(B, A)
9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2(1H)-onenon-polymer432.42Chemie (17G)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight341120.7
Non-Polymers*Number of molecules2
Total formula weight864.8
All*Total formula weight341985.5
*Water molecules are not included.

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PDB entries from 2024-11-13

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