4JSX

structure of mTORDeltaN-mLST8-Torin2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (B, A)	Serine/threonine-protein kinase mTOR	polymer	1174	134650.3	2	UniProt (P42345) Pfam (PF02259) Pfam (PF08771) Pfam (PF00454) Pfam (PF02260)	Homo sapiens (human)	FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, mTOR, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1
2	B, D (D, C)	Target of rapamycin complex subunit LST8	polymer	326	35910.1	2	UniProt (Q9BVC4) Pfam (PF00400)	Homo sapiens (human)	TORC subunit LST8, G protein beta subunit-like, Gable, Protein GbetaL, Mammalian lethal with SEC13 protein 8, mLST8
3	E, F (B, A)	9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2(1H)-one	non-polymer		432.4	2	Chemie (17G)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	341120.7
Non-Polymers*	Number of molecules	2
	Total formula weight	864.8
All*	Total formula weight	341985.5

*Water molecules are not included.