4JSX
structure of mTORDeltaN-mLST8-Torin2 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C (B, A) | Serine/threonine-protein kinase mTOR | polymer | 1174 | 134650.3 | 2 | UniProt (P42345) Pfam (PF02259) Pfam (PF08771) Pfam (PF00454) Pfam (PF02260) | Homo sapiens (human) | FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, mTOR, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1 |
2 | B, D (D, C) | Target of rapamycin complex subunit LST8 | polymer | 326 | 35910.1 | 2 | UniProt (Q9BVC4) Pfam (PF00400) | Homo sapiens (human) | TORC subunit LST8, G protein beta subunit-like, Gable, Protein GbetaL, Mammalian lethal with SEC13 protein 8, mLST8 |
3 | E, F (B, A) | 9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2(1H)-one | non-polymer | 432.4 | 2 | Chemie (17G) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 341120.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 864.8 | |
All* | Total formula weight | 341985.5 |