4JS8
Crystal structure of TTK kinase domain with an inhibitor: 401348
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual specificity protein kinase TTK | polymer | 281 | 32619.3 | 1 | UniProt (P33981) Pfam (PF00069) | Homo sapiens (human) | Phosphotyrosine picked threonine-protein kinase, PYT |
| 2 | B (A) | 4-(cyclohexylmethoxy)-3-{4-[(1-methylpiperidin-4-yl)oxy]phenyl}-2H-indazole | non-polymer | 419.6 | 1 | Chemie (1PF) | |||
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E, F (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 5 | G, H (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | I (A) | water | water | 18.0 | 73 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32619.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1008.1 | |
| All* | Total formula weight | 33627.4 |
